Participated in the MMFF 2017
Won People Choice Award in the MMFF 2017
Vice Ganda was involved in creating the costume design for his character. Vice wanted the costume to be vibrantly colored while also look good to appeal to children. Elements of the mobile game, Super Wings! (2015), which was popular at that time, as well as Sailor Moon (1995) was also incorporated in the costume.
First movie of Pia Wurtzbach since winning the Miss Universe 2015. It was also her first starring role after playing in a number of supporting role.
Joyce Bernal wanted color gold for the costume of Kweenie as nod to Pia Wurtzbach, being the titleholder of Miss Universe 2015.
Barna, the character of Karla Estrada, is a play between Barney from The Backyard Show (1988) and Darna (1951). Both Vice Ganda and Estrada has been toying with the name even years prior to the movie.
The character of Michael Flores, Professor Clean, is in reference to Mr. Clean, a brand name and mascot of an all-purpose cleaner. Both are bald.
Kris Aquino declined the offer to make a cameo appearance, playing an antagonistic role. She cited that the companies managing the brands she endorses may not be amicable to her playing a role of an antagonist.
Initially titled The Revengers, it was later changed to Gandarah N' Gwapito: The Revengers.
Principal photography began on July 2017.