This Preacher review contains spoilers.
Preacher Season 4 Episode 5
In the world of Preacher, characters seem to be drawn into situations not based off of free will, but divine providence. As Eugene often says, God has a plan, and we're all just following his plan no matter how directionless we might feel during a particularly trying moment. Certainly, Eugene is part of some sort of plan, even if that plan is simply for him to pray over the victims of the Saint of Killers as he murders his way across the world in pursuit of Jesse Custer.
Of all the characters, only The Saint and Jesse have a definitive goal in mind. The Saint wants Jesse dead, Jesse wants to stop the end of the world.