
| Fiona Apple | ... | Herself (segment "Criminal") |
 | Audioslave | ... | Themselves (segment "Cochise") |

| Beck | ... | Himself (segment "Devil's Haircut) |
 | Brian Bell | ... | Himself (segment "El Scorcho") (as Weezer) |
 | Chester Bennington | ... | Himself (segment "Faint") (as Linkin Park) |

| David Blaine | ... | Himself (segment "Criminal") |
 | Rob Bourdon | ... | Himself (segment "Faint") (as Linkin Park) |

| David Bowie | ... | Himself (segment "Jump, They Say") |
 | Peter Buck | ... | Himself (segment "Strange Currencies") (as R.E.M.) |

| Johnny Cash | ... | Himself (segment "Hurt") |
 | Chris Cornell | ... | Himself (segment "Cochise") (as Audioslave) |
 | Rivers Cuomo | ... | Himself (segment "El Scorcho") (as Weezer) |
 | Brad Delson | ... | Himself (segment "Faint") (as Linkin Park) |
 | Tom Dumont | ... | Himself (segment "Hella Good") (as No Doubt) |
 | Garrett Dutton | ... | Himself (segment "Cold Beverage") (as G. Love) |
 | Terry Ellis | ... | Herself (segment "Free Your Mind") (as En Vogue) |

| Mark Everett | ... | Himself (segment "Novocaine for the Soul") (as The Eels) |
 | Phoenix Farrell | ... | Himself (segment "Faint") (as Linkin Park) |
 | Flea | ... | Himself (segment "Can't Stop") (as Red Hot Chili Peppers) |
 | John Frusciante | ... | Himself (segment "Can't Stop") (as Red Hot Chili Peppers) |

| Vincent Gallo | ... | Himself (segment "99 Problems") |
 | Kim Gordon | ... | Herself (segment "Little Trouble Girl") (as Sonic Youth) |
 | Joseph Hahn | ... | Himself (segment "Faint") (as Linkin Park) |
 | Cindy Herron | ... | Herself (segment "Free Your Mind") (as En Vogue) |

| Janet Jackson | ... | Herself (segments "Scream" and "Got Til It's Gone") |

| Michael Jackson | ... | Himself (segment "Scream") |

| Mick Jagger | ... | Himself (segment "God Gave Me Everything") |
 | Jay-Z | ... | Himself (segment "99 Problems") |
 | Maxine Jones | ... | Herself (segment "Free Your Mind") (as En Vogue) |
 | Tony Kanal | ... | Himself (segment "Hella Good") (as No Doubt) |
 | Anthony Kiedis | ... | Himself (segment "Can't Stop") (as Red Hot Chili Peppers) |

| Lenny Kravitz | ... | Himself (segment "Are You Gonna Go My Way?") |
 | k.d. lang | ... | Herself (segment "Constant Craving") |
 | Linkin Park | ... | Themselves (segment "Faint") |

| Madonna | ... | Herself (segments "Rain" and "Bedtime Story") |
 | Mike Mills | ... | Himself (segment "Strange Currencies") (as R.E.M.) |
 | Tom Morello | ... | Himself (segment "Cochise") (as Audioslave) |
 | No Doubt | ... | Themselves (segment "Hella Good") |
 | Butch Norton | ... | Himself (as Eels) |
 | Q-Tip | ... | Himself (segment "Got Til It's Gone") |
 | Red Hot Chili Peppers | ... | Themselves (segment "Can't Stop") |
 | R.E.M. | ... | Themselves (segment "Strange Currencies") |
 | Trent Reznor | ... | Himself (segments "Closer" and "The Perfect Drug") (as Nine Inch Nails) |
 | Keith Richards | ... | Himself (segment "Wicked as it Seems") |
 | Dawn Robinson | ... | Herself (segment "Free Your Mind") (as En Vogue) |

| Chris Rock | ... | Himself |

| Rick Rubin | ... | Himself (segment "99 Problems") |
 | Mike Shinoda | ... | Himself (segment "Faint") (as Linkin Park) |
 | Chad Smith | ... | Himself (segment "Can't Stop") (as Red Hot Chili Peppers) |

| Shannyn Sossamon | ... | Herself (segment "God Gave Me Everything") |

| Gwen Stefani | ... | Herself (archive footage) |

| Ben Stiller | ... | Himself (segment "Romanekian") |

| Michael Stipe | ... | Himself (segment "Strange Currencies") (as R.E.M.) |

| Robin Williams | ... | Himself (segment "Romanekian") |
 | Adrian Young | ... | Himself (segment "Hella Good") (as No Doubt) |
 | Sonic Youth | ... | Themselves (segment "Little Trouble Girl") |